Application (Patent) No.:
CN202011118987.9
Public/Announcement No.:
CN112409179A
Applicator:
Wengyuan Guangye Qingyi Food Technology Co., Ltd Guangdong Guangye Qingyi Food Technology Co., Ltd
Inventor:
Du Yangji, Xu Jinxiong, Wei Na
Country Code:
CN440229
Summary:
The present invention discloses a purification method of menthyl lactate, including the following steps:(1) selecting a mixture containing menthyl lactate produced by the direct esterification reaction of menthol and lactic acid, and adding a low-polarity alkane, stir and extract;(2) wash the organic layer with alkaline saturated brine to neutrality, stand and layer, evaporate the organic solvent under reduced pressure to obtain the extract concentrate;(3) the extraction concentrate is dissolved in lower alcohol to prepare the alcohol solution of the extract, then the sample is loaded into the macroporous resin HP20 chromatography column, and then the gradient elution is carried out with different concentrations of lower alcohol, and the eluent is detected by GC, the menthyl lactate segment is combined and concentrated and the solvent is recovered to obtain the crude menthyl lactate;(4) the crude menthyl lactate is dissolved in an aqueous solution of isopropanol, filtered, the supernatant is cooled for crystallization, filtered, dry to obtain purified menthyl lactate. The purification method has high selectivity, high efficiency, low cost and high purity of menthyl lactate.
Menthyl lactate replenishes epidermal moisture, is easily absorbed by the skin, and cools the skin after application, but cannot be used for a long time.
1. Supplement epidermal moisture: the main ingredient in menthol lactate is menthol lactate, which is suitable for oily skin and wrinkled skin. After application, it can supplement the moisture on the skin surface.
2, easy to be absorbed by the skin: this ingredient has less adverse reactions to the skin, applied to daily chemical products and oral products, easy to be absorbed by the skin.
3, skin cool: This product is a kind of cooling agent, after the application can make the skin more cool.
In addition, it can also be used to improve skin pigmentation.